Home » News & Facts » 10 Nutrient Deficiencies that Can Cause Depression

10 Nutrient Deficiencies that Can Cause Depression

1 of 3

Feeling down at times is a normal part of life, but feeling miserable and hopeless on a consistent basis could mean that you are depressed.

Depression is a mood disorder that causes persistent feelings of sadness, anger and a general loss of interest in life that interferes with a person’s day-to-day activities.

Other signs and symptoms of depression include loss of appetite, significant weight loss or weight gain, changes in sleep pattern, lack of energy, difficulty concentrating, and unexplained aches and pains.


Some of the causes and risk factors for depression include social isolation, stress, family history of depression, relationship problems, financial strain, childhood trauma or abuse, alcohol or drug abuse and certain health conditions.

Nutritional deficiencies are also likely contributing to the problem. Researchers have found that people suffering from depression and mood disorders are deficient in not just one but several nutrients.

Always remember that the food you eat feeds the brain as well as the body. As the brain accounts for most of your metabolic demands, it needs constant nourishment.

nutrient deficiencies that cause depression


Here are the top 10 nutrient deficiencies that can cause depression.

1. Omega-3 Fatty Acids

Omega-3 fatty acids have numerous health benefits. They play a key role in the development and functioning of the central nervous system.

While omega-3 DHA (docosahexaenoic acid) is critical for brain cell structure, EPA (eicosapentaenoic acid) helps with neuron function and even reduces inflammation.

In addition to this, omega-3 fatty acids can help lower bad cholesterol levels and contribute to overall heart health.

A 2007 study published in Medical Hypotheses reports that omega-3 fatty acid deficiency in major depressive disorder is due to the interaction between diet and a genetically determined abnormality in phospholipid metabolism.

In a 2014 study published in Oxidative Medicine and Cellular Longevity, researchers reported that proper intake of omega-3 PUFA (polyunsaturated fatty acids) and dietary interventions including omega-3 PUFA supplements can help prevent and treat depression.

To supply your body with an adequate amount of omega-3 fatty acids, consume more flaxseeds, fatty fish like salmon, walnuts and omega-3 fortified eggs. You can also take an omega-3 fatty acid supplement, after consulting your doctor.

2. Vitamin D

Vitamin D deficiency has been linked to depression as well as dementia and autism. This vitamin helps in the production of serotonin, the brain hormone associated with mood elevation and happiness.

An adequate level of serotonin helps prevent and treat mild depression. In addition, vitamin D is important for the immune system and bone health.

A 2010 study published in the International Journal of Mental Health Nursing notes that vitamin D deficiency is common among the elderly, adolescents, obese individuals, and those with chronic illnesses. These people are also reported to be at higher risk for depression.

Also, in a 2014 study published in Medical Hypotheses, researchers found a link between seasonal affective disorder (SAD) and a lack of sunlight.

Researchers pointed out that vitamin D is involved in the synthesis of serotonin and dopamine within the brain, both chemicals that are linked to depression.

By spending time in the sun, you can help your body make vitamin D. Go for regular walks in the early morning for 15 to 20 minutes daily. You can also take a vitamin D supplement, after consulting your doctor.


3. Magnesium

Magnesium is another important nutrient, the deficiency of which can lead to depression. It helps activate enzymes needed for serotonin and dopamine production.

It also influences several systems associated with development of depression. In addition, it keeps your bones healthy, reduces anxiety and lowers blood pressure, to name a few.

A 2006 study published in Medical Hypotheses reports that magnesium deficiency is the cause of most major depression and related mental health problems, including IQ loss.

A 2013 study published in Pharmacological Reports also throws light on the beneficial effect of magnesium in the management of depression.

To prevent magnesium deficiency, eat foods rich in magnesium, such as seaweed, almonds, avocados, bananas, beans, pumpkin seeds, tofu, soy milk, whole grains, bran and green leafy vegetables.

Also, avoid excessive intake of alcohol, salt, coffee, sugar and soda, all of which can lower your magnesium level.

4. Zinc

Zinc is another essential micronutrient that your body needs to help reduce the risk of depression. This nutrient plays a key role in neuronal functions.

It boosts neurotransmitter production and functioning. It is even involved in over 250 separate biochemical pathways that support the functions of different organs.

A 2011 study published in Progress in Neuro-psychopharmacology & Biological Psychiatry explained the role of zinc in neurodegenerative inflammatory pathways in depression.

Also, a 2013 study published in Biological Psychiatry notes that depression is associated with a lower concentration of zinc in peripheral blood.

Eating zinc-rich foods can help correct this deficiency. Some good sources include red meat, eggs, shellfish, pulses, legumes, nuts, seeds, whole-grain cereals and dairy products. You can also opt for supplements, after consulting your doctor.

5. Selenium

Selenium is also essential to brain functioning and helps improve mood and depressive symptoms. Moreover, selenium plays an important role in proper thyroid functioning. A healthy thyroid is important for mental health.

A 2012 study published in Complementary Therapies in Medicine notes that lower dietary selenium intakes are associated with an increased risk of major depressive disorder.

Selenium’s role as an antioxidant and as a constituent of selenoproteins helps in the prevention and management of depression.

Similarly, a 2015 study published in the Journal of Nutrition reports that optimal serum selenium concentrations are associated with lower depressive symptoms and negative mood among young adults.

You can get selenium from dietary sources like Brazil nuts, lean meats, seafood, beans, peas, eggs, turkey, chicken and shellfish.

6. Vitamin B12

B vitamins are important for overall physical as well as mental health. In particular, vitamin B12 helps in the formation of red blood cells and maintenance of a healthy nervous system.

In fact, its deficiency may be the key reason behind depression. In addition, B12 helps lower levels of homocysteine, a by product of protein metabolism. Elevated levels of homocysteine increase the risk for depression.

A 2009 study published in the Journal of Clinical Psychiatry illustrates the importance of considering the possibility of B12 deficiency, especially among the elderly suffering from depression.

Another 2013 study published in the Open Neurology Journal highlights the importance of vitamin B12 supplementation in the treatment of major depressive disorder.

Patients treated with vitamin B12 supplementation with antidepressants showed significant improvement in depressive symptoms.

To avoid deficiency of vitamin B12, eat foods like lean meats, fish, poultry, eggs, dairy products, nutritional yeasts, fortified cereals and soy milk. You can also consider taking a vitamin B supplement daily, after consulting your doctor.

10 Nutrient Deficiencies that Can Cause Depression was last modified: October 1st, 2017 by Top10HomeRemedies
1 of 3

3 thoughts on “10 Nutrient Deficiencies that Can Cause Depression”

Leave a Reply

Your email address will not be published. Required fields are marked *